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gastrointestinal

Non-Celiac Gluten Sensitivity

Digestive and other symptoms triggered by gluten in people who don't have celiac disease or wheat allergy.

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Overview

Non-celiac gluten sensitivity (NCGS) is a condition where eating gluten — a protein found in wheat, barley, and rye — causes symptoms similar to celiac disease, but without the intestinal damage or antibodies that characterize celiac. Symptoms typically appear hours to days after eating gluten and improve on a gluten-free diet. The exact mechanism is not fully understood, and some people may actually be reacting to other components of wheat (like FODMAPs).

Symptoms

Common Symptoms

  • Bloating and gas
  • Abdominal pain
  • Diarrhea or constipation
  • Fatigue
  • Brain fog or difficulty concentrating
  • Headaches
  • Joint pain
  • Skin problems
  • Anxiety or depression
  • Unlike celiac disease: no intestinal damage detected on biopsy

Diagnosis

Diagnosis typically involves clinical evaluation, medical history, blood tests, and appropriate imaging studies. A healthcare provider will assess symptoms, order relevant laboratory work, and may refer to a specialist for confirmation.

Treatments

Treatment depends on the underlying cause and severity. Options may include medication, lifestyle modifications (diet, exercise, stress management), and ongoing monitoring. Always work with a qualified healthcare provider to develop an appropriate treatment plan.

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