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gastrointestinal

Non-Alcoholic Fatty Liver Disease

Fat accumulation in the liver not caused by alcohol, which can progress to inflammation and liver damage.

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Overview

Non-alcoholic fatty liver disease (NAFLD) is a condition where excess fat builds up in the liver of people who drink little or no alcohol. It is the most common liver disease worldwide, affecting about 25% of adults. NAFLD is strongly linked to obesity, type 2 diabetes, and metabolic syndrome. In some people, it progresses to non-alcoholic steatohepatitis (NASH), which can cause liver scarring (cirrhosis) and liver failure. Early-stage NAFLD is reversible with lifestyle changes.

Symptoms

Common Symptoms

  • Often no symptoms in early stages
  • Fatigue
  • Discomfort or pain in the upper right abdomen
  • Enlarged liver (felt on exam)
  • In advanced stages: jaundice, ascites, easy bruising, confusion
  • Diagnosis: often found on routine blood tests (elevated liver enzymes) or imaging

Diagnosis

Diagnosis typically involves clinical evaluation, medical history, blood tests, and appropriate imaging studies. A healthcare provider will assess symptoms, order relevant laboratory work, and may refer to a specialist for confirmation.

Treatments

Treatment depends on the underlying cause and severity. Options may include medication, lifestyle modifications (diet, exercise, stress management), and ongoing monitoring. Always work with a qualified healthcare provider to develop an appropriate treatment plan.

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